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Xeomin

Xeomin

Xeomin (incobotulinumtoxinA), made by Merz Pharmaceuticals,  is approved by the US FDA for the treatment of adults with cervical dystonia or blepharospasm.  Xeomin is made from the bacteria that causes botulism (just like Botox). Botulinum toxin blocks nerve activity in the muscles, causing a temporary reduction in muscle activity.

FDA approval of XEOMIN,  was based on the results of two U.S. clinical trials. A study cited in the Journal of Neurological Sciences on the efficacy and safety of XEOMIN found it showed “non-inferiority” to Botox when used in the same doses to treat cervical dystonia. It concluded that XEOMIN is a safe and effective treatment for the disorder.

Now that Xeomin is available and FDA approved, doctors can use it to treat the same facial lines treated by Botox and Dysport, including frown lines, crow's feet and forehead wrinkles.  Xeomin has been used extensivly in European countries. 

Better or worse then Botox, Dysport?  How does it compare to Botox and Dysport?

Xeomin is the first one that does not need to be refrigerated before use, which may simplify distribution. Xeomin is also has no additives, it's a pure form of just botulinum toxin type A. This may mean that there is less risk of developing antibodies against Xeomin than other available neurotoxins (i.e Botox, Dysport). The body develops antibodies in response to a foreign invader and attacks. In theory, antibodies could prevent a neurotoxin from having its desired effects. The effects of Xeomin occur within one week, and the results last from three to six months, making it comparable to Botox in terms of both onset and duration of action. Xeomin should not be used interchangeably with other botulinum products.  

What are the risks?

There is a risk that all botulinum toxin products may spread from the area where they were injected to other parts of the body, causing potentially life-threatening swallowing and breathing problems. This was predominantly seen in children treated with Botox off-label for cerebral palsy. These issues have not been reported among people who received botulinum products for cosmetic uses or to treat blepharospasm.

Other risks may include bleeding and bruising at the injection site and allergic reactions such as itching, swelling or shortness of breath. Your doctor should discuss all the potential risks of this procedure with you during your consultation.

When Xeomin is used to treat cervical dystonia, side effects include neck pain, muscle weakness, injection site pain and musculoskeletal pain. When used to treat blepharospasm, the most common side effects of Xeomin were eyelid sagging, dry eye, dry mouth, diarrhea, headache, visual impairment, shortness of breath (dyspnea), and upper respiratory infections.

How much does Xeomin cost?

Currently Xeomin is less expensive than Botox or Dysport, but it will change soon as the use of Xeomin will become more frequent due to its purity and less likely risk of anitibody production.  

 

NOTE: 

Did you know that Xeomin is pure with less impurities than Botox, Dysport?

Xeomin® is an effective and well-tolerated treatment for facial wrinkles and is approved for the treatment of glabellar frown lines in many countries
     Xeomin differs from other commercially available botulinum toxin type A products as it is free from complexing proteins and other impurities
     Complexing proteins have no therapeutic effect and do not prevent the active neurotoxin from diffusing and may lead to an increased risk of antibody formation
     Xeomin is highly stable and can be stored at room temperature
     Xeomin has a higher specific biological activity than other available botulinum toxin type A preparations, such as  (Botox® / Vistabel) or (Dysport® / Azzalure®)

 NewSkin Laser Center has great pricing now on Xeomin.  Check our price list. 

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